A recent publication showing that human adipose derived stem cells adhere to damaged tissue within a knee joint and persist. Lipogems is an adipose fat graft technology that preserves the vascular stromal niche, thereby delivering mechanical and bio-active elements in treating the painful knee.
The administration of adipose fat graft mechanical, regenerative and cellular solutions is focussed on relieving pain and restoring functional abilities, and quality of life. These orthopedic applications of adipose fat graft technologies to help regenerate and restore tissues is fast becoming the catalyst for a paradigm shift in how we approach the orthopedic patient. The science behind tissue and cellular medicine is irrefutable.
In vivo human adipose-derived mesenchymal stem cell tracking after intra-articular delivery in a rat osteoarthritis model.
Since haMSCs after IA injection were mainly concentrated in the joint area, our next step was to try and confirm the therapeutic efficacy at 70 days after the cell therapy to collaborate the biodistribution findings. In the normal group, HE staining showed that the surface of the articular cartilage was smooth and intact while in the DiD control group (surgery-induced OA without cell treatment), articular cartilage exhibited rough borders.